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In a dark room or with the eyes closed, brief flashes of light are seen when the eyes are moved
    Differential Diagnosis[Top] [Nav]
optic neuritis / multiple sclerosis
    Discussion -- not available online[Top] [Nav]
    Update Comments[Top] [Nav]
  • A selection from JAMA's "Questions and Answers" column: a 63 year old female physician with end-gaze phosphenes timed to her heart beat (arterial pulsation). [101]
    Footnotes in Print Edition[Top] [Nav]
    (1) Movement phosphenes in optic neuritis: a new clinical sign.
  Davis FA, Bergen D, et al.   Neurology 1976 Nov;26(11):1100-4.  Pubmed+Abstract  Similars
    (2) McAlpine's Multiple Sclerosis.
  Matthews WB, et al. Edinburgh: Churchill Livingstone, 1985: 220.
    (3) The amateur scientist. About phosphenes: luminous patterns that appear when the eyes are closed.
  Walker J.   Scientific American. 1981;244(5):174-184.
    (4) Lightning streaks of Moore: a cause of recurrent stereotypic visual disturbance.
  Zaret BS.   Neurology 1985 Jul;35(7):1078-81.  Pubmed+Abstract  Similars
    (5) [This footnote was a comment, not a reference.]
    New References[Top] [Nav]
Phosphenes
    101.Visual sensation of light.
  Guyton DL.   JAMA. 1995;273:1493.
Lhermitte sign
    102.Adverse Mechanical Tension in the Central Nervous System: Relief by Functional Neurosurgery.
  Breig A. New York: Wiley, 1978: 110-111, 177.
    103.Lhermitte's sign in cobalamin (vitamin B12) deficiency.
  Butler WM, Taylor HG, et al.   JAMA 1981 Mar 13;245(10):1059.  Pubmed  Similars
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    ©1986-2000 John Sotos, MD. All rights reserved.  Last updated 16:34 PDT on July 4, 2000.[Top]

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