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Muscular pain 5 to 10 minutes after starting exercise
    Differential Diagnosis[Top] [Nav]
McArdle disease (myophosphorylase deficiency)
    Discussion -- not available online[Top] [Nav]
    Erratum in printed version[Top] [Nav]
       *There is a disorder of glycogenolysis that produces lactate in the ischemic forearm test. See below.
    Update Comments[Top] [Nav]
  • Persons with the adult form of acid maltase deficiency produce lactate during the ischemic forearm test. [102]
    Footnotes in Print Edition[Top] [Nav]
    (1a) Myopathy in McArdle's syndrome. Improvement with a high-protein diet.
  Slonim AE, Goans PJ.   N Engl J Med 1985 Feb 7;312(6):355-9.  Pubmed  Similars
    (1b) McArdle's disease in the 1980s [editorial].
  Layzer RB.   N Engl J Med 1985 Feb 7;312(6):370-1.  Pubmed  Similars
    (2a) McKusick 232600 = McArdle disease (autosomal recessive).
    (2b) McKusick 153460 = McArdle disease (autosomal dominant).
    (3) Handbook of Clinical Neurology.
  Vinken PJ, Bruyn GW. Amsterdam: North Holland: 1979;41:175-234 [chapter = Di Mauro S. Metabolic myopathies].
    New References[Top] [Nav]
    101.A standardized forearm ischemic exercise test.
  Munsat TL.   Neurology 1970 Dec;20(12):1171-8.  Pubmed  Similars
    102.Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1986. A 29-year-old woman with slowly progressive proximal-muscle weakness.
  N Engl J Med 1986 Sep 11;315(11):694-701.  Pubmed  Similars
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    ©1986-2000 John Sotos, MD. All rights reserved.  Last updated 16:34 PDT on July 4, 2000.[Top]

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