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Arthralgias in a woman with breast scars
    Differential Diagnosis[Top] [Nav]
postmammoplasty connective tissue disease (human adjuvant disease)
    Discussion -- not available online[Top] [Nav]
    Erratum in printed version[Top] [Nav]
       *[footnote 2b] Volume is 17, not 47.
    Update Comments[Top] [Nav]
  • Non-mammary-silicone is card AB-003. [101]
  • The FDA decided in 1988 not to ban silicone breast implants. [107]
  • Does not address syndromic associations of hypomastia, e.g. mitral valve prolapse [NEJM 1983;309:1230-1232]. [110]
  • Is this another type of cosmetic implant surgery with immunological side effects? [111]
  • Men are not immune from leaking silicone syndromes. [112]
  • Discusses a lawsuit alleging babies of silicone-implanted mothers are injured by transplacental passage of silicone and by silicone in mother's milk. But one physician notes there is more silicone in proprietary milk products than in breast milk and that silicone is a major constituent of plastic nipples on baby bottles. [113]
    Footnotes in Print Edition[Top] [Nav]
    (1) Systemic reactions to silicone implants is certainly no longe a zebra!
    (1a) Silicone mastitis in "topless" waitresses and some other varieties of foreign-body mastitis.
  Symmers WS.   Br Med J 1968 Jul 6;3(609):19-22.  Pubmed  Similars
    (1b) Toxicology of silicones.
  Helal B.   Br Med J 1968 Jul 20;3(611):184-5.  Pubmed  Similars
    (2a) Safety of silicone breast prostheses.
  Anonymous.   FDA Drug Bulletin. 1989;19(1):2-3.
    (2b) Silicone and rheumatic diseases.
  Endo LP, Edwards NL, et al.   Semin Arthritis Rheum 1987 Nov;17(2):112-8.  Pubmed+Abstract  Similars
    (3) Scleroderma after cosmetic surgery: four cases of human adjuvant disease.
  Kumagai Y, Abe C, et al.   Arthritis Rheum 1979 May;22(5):532-7.  Pubmed+Abstract  Similars
    (4) Post-mammoplasty connective tissue disease.
  van Nunen SA, Gatenby PA, et al.   Arthritis Rheum 1982 Jun;25(6):694-7.  Pubmed  Similars
    (5) Post-mammoplasty human adjuvant disease.
  Byron MA, Venning VA, et al.   Br J Rheumatol 1984 Aug;23(3):227-9.  Pubmed+Abstract  Similars
    New References[Top] [Nav]
    101.Non-mammary-silicone is card AB-003.

Clinical papers
    102.A clinical and immunologic evaluation of women with silicone breast implants and symptoms of rheumatic disease [see comments].
  Bridges AJ, Conley C, et al.   Ann Intern Med 1993 Jun 15;118(12):929-36.  Pubmed+Abstract  Similars
    103.Systemic sclerosis after augmentation mammoplasty with silicone implants.
  Varga J, Schumacher HR, et al.   Ann Intern Med 1989 Sep 1;111(5):377-83.  Pubmed+Abstract  Similars
    104.Human adjuvant disease. A new cause of chylous effusions.
  Walsh FW, Solomon DA, et al.   Arch Intern Med 1989 May;149(5):1194-6.  Pubmed+Abstract  Similars
    105.Sclerodermalike esophageal disease in children breast-fed by mothers with silicone breast implants [see comments] [published erratum appears in JAMA 1994 Sep 14;272(10):770].
  Levine JJ, Ilowite NT.   JAMA 1994 Jan 19;271(3):213-6.  Pubmed+Abstract  Similars

Epidemiological papers
    106.Silicone breast implants and the risk of connective-tissue diseases and symptoms [see comments].
  Sanchez-Guerrero J, Colditz GA, et al.   N Engl J Med 1995 Jun 22;332(25):1666-70.  Pubmed+Abstract  Similars

    107.Silicone breast implants on trial.
  Anonymous.   Science News. 1988;134:380.
    108.Do breast implants cause systemic disease? Science in the courtroom [editorial; comment] [see comments].
  Angell M.   N Engl J Med 1994 Jun 16;330(24):1748-9.  Pubmed  Similars
    109.Shattuck Lecture--evaluating the health risks of breast implants: the interplay of medical science, the law, and public opinion [see comments].
  Angell M.   N Engl J Med 1996 Jun 6;334(23):1513-8.  Pubmed  Similars
    110.Characteristics of women with and without breast augmentation [see comments].
  Cook LS, Daling JR, et al.   JAMA 1997 May 28;277(20):1612-7.  Pubmed+Abstract  Similars
    111.Association between bovine collagen dermal implants and a dermatomyositis or a polymyositis-like syndrome [see comments].
  Cukier J, Beauchamp RA, et al.   Ann Intern Med 1993 Jun 15;118(12):920-8.  Pubmed+Abstract  Similars
    112.Silicone gel-filled testicular prosthesis and systemic disease.
  Pidutti R, Morales A.   Urology 1993 Aug;42(2):155-7.  Pubmed+Abstract  Similars
    113.Child claim over hazards of silicone breast implant planned in UK [news].
  Moore P.   Lancet 1998 Jan 31;351(9099):349.  Pubmed  Similars
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    ©1986-2000 John Sotos, MD. All rights reserved.  Last updated 16:34 PDT on July 4, 2000.[Top]

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