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Decrease of the PR interval over several years
    Differential Diagnosis[Top] [Nav]
Fabry disease
    Discussion -- not available online[Top] [Nav]
    Update Comments[Top] [Nav]
  • "Clearly, patients with cardiac symptoms (angina, exercise intolerance, and electrocardiographic changes) but normal coronary arteries, heart size, and hemodynamic findings present a frequent and usually unresolved problem to every cardiologist. Thus, Fabry's [sic] disease should be considered as a possible cause of otherwise unexplained cardiac symptoms." [102]
  • Sinus tachycardia, short PR interval, lateral Q waves, and tall anterior R waves are typical of Duchenne muscular dystrophy. [103]
    Footnotes in Print Edition[Top] [Nav]
    (1) Accelerated atrioventricular conduction in Fabry's disease: a case report.
  Rowe JW, Caralis DG.   Angiology 1978 Jul;29(7):562-8.  Pubmed+Abstract  Similars
    (2) The Metabolic Basis of Inherited Disease. 5th ed.
  Stanbury JB, et al. New York: McGraw-Hill, 1983: 906-944.
    (3) Short PR interval and narrow QRS complex associated with pheochromocytoma: electrophysiologic observations.
  Huang SK, Rosenberg MJ, et al.   J Am Coll Cardiol 1984 Mar;3(3):872-5.  Pubmed+Abstract  Similars
    New References[Top] [Nav]
    101.The abbreviated PR interval of Fabry's disease.
  Roudebush CP, Foerster JM, et al.   N Engl J Med 1973 Aug 16;289(7):357-8.  Pubmed  Similars
    102.An atypical variant of Fabry's disease with manifestations confined to the myocardium.
  von Scheidt W, Eng CM, et al.   N Engl J Med 1991 Feb 7;324(6):395-9.  Pubmed  Similars
    103.Palpitation and abnormal ECG in muscular dystrophy.
  Hancock EW.   Hosp Pract (Off Ed) 1989 Jul 15;24(7):21, 24.  Pubmed  Similars
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    ©1986-2000 John Sotos, MD. All rights reserved.  Last updated 16:34 PDT on July 4, 2000.[Top]

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